Mapping social enterprises: past approaches, challenges and future directions

Sarcoma Immunotherapy: Past Approaches and Future Directions

Sarcomas are heterogeneous malignant tumors of mesenchymal origin characterized by more than 100 distinct subtypes. Unfortunately, 25-50% of patients treated with initial curative intent will develop metastatic disease. In the metastatic setting, chemotherapy rarely leads to complete and durable responses; therefore, there is a dire need for more effective therapies. Exploring immunotherapeutic...

Corrigendum to “Sarcoma Immunotherapy: Past Approaches and Future Directions”

[This corrects the article DOI: 10.1155/2014/391967.].

Clinical reasoning assessment through medical expertise theories: past, present and future directions

  Exploration into the concept of "medical expert" dates back to more than 50 years ago, yet yielding three leading theories in the area of clinical reasoning, namely, knowledge structure, hypothetic-deductive, and dual process. Each theory defines “medical expert” in a dissimilar way. Therefore, the methods of assessment through which the experts are identified have been changed during the tim...

Litigation Holds: Past, Present, and Future Directions

Electronically Stored Information (ESI) first became a serious litigation issue in the late 1990s, and the first attempts to determine best practices did not occur until the early 2000s. As best practices developed, the litigation hold to prevent routine destruction of documents and to preserve documents relevant to litigation came into existence. The duty to preserve ESI is triggered when liti...

Organizational Ecology: Past, Present, and Future Directions